Roundleaf bittersweet is a woody vine that can grow over 60 feet long. It has rounded leaves that are toothed and have pointed tips. The leaves are alternately arranged along the stem. They turn yellow in the fall. This plant is dioecious, which means there are separate male and female plants. Female plants will produce axillary clusters of green flowers in late spring to early summer. Axillary flowers occur along the stem of the plant, rather than at the tip of a branch. The flowers are replaced by green fruits in the summer that mature into yellow-orange capsules. The capsules break open in fall to winter to reveal a red fruit inside.
There is a native species called American bittersweet, Celastrus scandens, that looks similar. The flowers of American bittersweet occur in terminal clusters, meaning they are only found at the tip of a branch, rather than along the stems. The capsules of American bittersweet are dark orange in color, rather than more yellow orange in roundleaf bittersweet.